|Viread in combo
Aug 30, 2002
From what I have read, Viread sounds like a good option for my first attempt at treatment. My doctor has never prescribed it before and doesn't know much about it. Should I just stick with what he knows? What would a good combination be including this drug?
| Response from Dr. Wohl
If tenofovir came out 6 years ago, it would probably be one of the most commonly used antiretroviral on the planet. Instead, as a newcomer, it must prove itself against the likes of older, more established drugs like AZT, d4T and ddI.
Clinicians often get set in their ways and are reluctant to try something new unless there is a clear justification for vearing from the familiar. The first evidence that tenofovir was a potent and well tolerated agent came from studies where it was used as a salvage or 'last ditch effort' therapy. Treaters have become more accustomed to using the drug in this situation.
Only recently have data emerged demonstrating the drug can be used as a first line agent with just as much success as one of the most common combos out there (d4T/3TC/efavirenz). The major study comparing tenofovir to d4T when combined with these other two drugs was designed to show whether or not the combos tested were similiar in effectiveness and not to see how much better one was over the other. I think over time this study may show that not only is tenofovir at least as potent and effective as d4T but that it may end up having less toxicity.
I think tenofovir is a very reasonable choice as a first line agent and given the data regarding the potency of 3TC and efavirenz (and that all can be given once a day) see this as a nice combination for someone starting on therapy. Good luck-DW
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Tingling In Fingers Could I Have AIDS
- Odds Of Getting HIV Picking Your Nose
- Sex With A Prostitute Negative At 3 Months
- Achy Balls After Touching Period Blood Worried I Have HIV
- Black Spots After Vaginal Sex Without Condom Does It Mean I Have HIV
- Bloody Pee After Unprotected Vaginal Sex Worried I Have HIV
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.