Please Note: Due to volume considerations, not all questions can be answered. Questions most likely to be answered will be those of general interest to a broad group of visitors to this forum. Questions pertaining to a specific case; requests for diagnosis, medical advice, or second opinion; or requests for opinions about untested alternative therapies will generally not be answered.
La participacion del Doctor Steve Natterstad en el
Foro de Tratamientos fue hecho posible gracias a Boehringer Ingelheim.
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hla
Apr 4, 2008
hola,soy positivo desde el año 1990 estoy en 1.100 cd4 y c.v indetectable,sufro de una pequeña lipoatrofia y mi medico me ha recomendado un cambio de medicacion pero antes debo hacerme la prueba de HLA. Podria decirme en que consiste dicha prueba? gracias
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Respuesta del Dr. Natterstad
Hola,
Estás hablando de la prueba de detección del gen HLA-B*5701, la presencia del que se asocia con un riesgo aumentado de desarrollar una reacción de hipersensibilidad a abacavir (Ziagen), un nucleósido. Abacavir, como tenofovir (Viread), se asocia con la lipoatrofia (pérdida de grasa en la cara, brazos, glúteos y piernas) con mucho menos frecuencia que con otros nucleósidos, en concreto d4T (Zerit) y AZT (zidovudina, Retrovir, Combivir, Trizivir). Si tu médico está contemplando abacavir como un componente de un nuevo régimen para ti, entonces sí, esta prueba es definitivamente conveniente.
Mucha suerte y un fuerte abrazo.
Dr. Steve
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