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bactrim and kidney problems?
Dec 2, 2001

My friend takes viracept, epivir, zerit and bactrim (prophylaxis) 2x/day, I believe. He reports that he has stopped taking the bactrim at times because he believes it causes kidney pain he experiences. The bactrim is very important right now, as his t cells have dropped to 150. Could there be a connection? I realize the other alternatives to Bactrim are not as effective. Are there environmental steps he can take to reduce his exposure to PCP? Thank you.

Response from Dr. Henry

The sulfa part of Bactrim can occasionally cause some kidney problems. Taking a smaller dose (single strength once daily) and increasing water intake usually is helpful. You are correct-Bactrim is the much preferred drug in this situation.


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