|BMS & Lipodistorphy
Oct 31, 2001
Will the new PI from BMS have come without the possibility of Lipodistorphy? I mean what I hear it does not casuse a rise in lipids so I am assuming it will be ok.
| Response from Dr. Henry
Limited data so far does suggest that the BMS protease inhibitor in development (atazanavir) has not been linked to the rises in cholesterol/triglycerides seen with some of the other protease inhibitors. I have not seen much regarding change in body fat distribution. There is hope that atazanavir will hold up as a PI that is fat/lipid friendly which would be an attractive feature along with once a day dosing. More experience with the drug will be necessary to validate those early observations. KH
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