Jul 11, 2001
Dr Henry, What neurological disorders would manifest themselves early on in hiv infection.You have mentioned transient problems in a previous response, please could you be more specific.Also will you comment on my problems which are still on going 16 weeks after a possible exposure. 1/.cold skin sensations which migrate around my body but are mostly in my legs.My legs actually feel cold to touch. 2/.constant multiple muscle twitches in my feet thighs and calves at rest, but no loss in muscle strength or aches. 3/.twitching finger it has a mind of its own. 4/.burning sensations in my skin, plus altered awareness of heat and cold.(hot feels ok but cold feels colder than it should. 5/.funny taste in mouth, on tip of my tongue especially. 6/.and lastly a weird one this, my left ear goes really hot for maybe 10 minutes then goes back to normal.
Have you seen any of the problems listed in hiv infected individuals, or might they be caused by stress and anxiety? I tested elisa neg at 11 weeks and am awaiting the results of a 16 week test, do you think I will test poz with these on going symptoms, and do you regularly come across people testing poz after 11 weeks or would that be highly unlikely. I would appreciate your opinion on these matters thankyou.
Response from Dr. Henry
The most common neurologig manifestations of primary HIV seroconversions syndrome are:
muscle or joint pain in about 50% encephalopathy (brain involvement with headache and other CNS findings often mimicing aseptic menigitis)) in around 8% peripheral neuropathy 8%
The symptoms you described would be very unusual to be associated with HIV seroconversion. With a negative HIV antibody test at 11 weeks, it is extremely unlikely that those symptoms are related to HIV infection. KH
RNA PCR vs. DNA PCR
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