Treatment Regimens for New HIV Dx.
May 16, 2000
Which sort of therapy regimen would newly diagnosed patients benefit from? The trend seems to be placing patients on three nucleosides and sparing the PI class and NNRTI class altogether.
Response from Dr. Henry
There is no one good starting regimen. A recent large analysis looking at > 20 studies of newly treated patients found overall that success rates were similar for three drug regimens whether one used a protease inhibitor, a non-nuke, or 3 nukes. Different people are in different camps on that but there is no one right answer. Long term data is disturbingly absent. I recommend an individualized approach between a knowledgeable patient and HIV expert who has access to clinical studies often addressing these types of questions. Long term treatment options and safety and tolerability of the regimen is just as important as the antiviral effectiveness. Keith Henry, M.D.
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