Lowering HAART Induced Cholesterol
Jun 10, 2001
Hi, Since going on a HAART regime of Videx EC, Crixivan, Combivir and Norvir, I have experienced increases in cholesterol and triglycerides. We first tried 20 mg. of Pravachol which had no effect. For five weeks, I have been on an increased dosage to 40 mg. Total cholesterol has barely lmoved, from 260 to 261, but the good has gone from 38 to 42 and triglycerides have come down from 430 to 202. Bad cholesterol is at 178 and a reading could not be taken before. My doctor now wants to try 40 mg. Lipitor in lieu of Pravachol. Is this likely to produce better results? Thank you. Gary
Response from Dr. Henry
Atorvastatin is usually more effective in this setting partly due to the fact that atorvastatin levels may be increased by the PIs (esp Norvir). I would recommend starting on a lower dose of atorvastatin (ie 20 mg). Fenofibrate maybe effective at reducing the triglycerides. Often the bad cholesterol level is hard to measure in the face of high triglycerides so special testing has to be done. There maybe some increased risk for muscle or liver toxicity when these drugs are used together so that needs to be monitored. KH
Get Email Notifications When This Forum Updates or Subscribe With RSS
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.