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CD 4 Build up
Mar 19, 2014

I have a friend whose CD 4 count was 1 and VL 230000 at the time of starting on medication (efavirenz) in January. How long might it take to build up the CD4 cells and reduce the VL?

Response from Dr. Henry

For the HIV level it may take up to 3-6 months for the HIV level to reach standard level of detection (< 50 copies) when starting that high assuming no resistance and good adherence to the medications. CD4 recovery is more variable with factors including age, CD4 nadir (1 is low), genetics, level of scarring in lymph tissue, size of active thymus gland, degree of onging of inflammation all influencing CD4 recovery. In general the lower the CD4 count the longer it takes to reach more reassuring levels (ie > 200 or > 350). KH



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