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EMTRICITABINE / LAMIVUDINE
Sep 8, 2013

hello doctor, frequently i have heard these two molecules have completely same profile regarding many important things like drug resistance profile, side effects, pharmacokinetics etc. so, can one choose any of them in their first regimen? which one would you prefer, a (tenofovir/lamivudine/efavirenz) or (tenofovir/emtricitabine/efavirenz)? I n one article i found emergence of drug resistance is more with lamivudine (M184V). for ur info, lamivudine based regimens cost $12/month less than emtricitabine based ART in my country. from ur experience,how long this one first line regimen work for one patient based on complete adherence? Regards.

Response from Dr. Henry

Emtricitabine may be slightly preferred from HIV standpoint but if more expensive then lamivudine may be a better choice if emtricitabine is more than your budget can handle. Both are good choices in general. KH



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