|Is Odimune safe during pregnancy?
Apr 16, 2013
I am a pregnant woman and HIV positive. I have just received my first batch of Odimune tablets and want to know whether it is safe. The enclosed leaflet warns that Odimune is not recommended for pregnant or breastfeeding women. I don't know what to do.
Response from Dr. Henry
Odimune (Atripla in US)is generally not recommended in pregnancy (particularly first trimester) due to concerns about fetal malformations from efavirenz.. There is a signal for fetal problems in some studies but other studies looking at pregnancy outcomes for women on Atripla have not observed a major problem. When there are good alternatives most often an different more pregnancy safe regimen is often preferred. Nonetheless it seems like more experts/patients are becoming more comfortable using Atripla in pregnancy. Bottom line-jury is still out-see following link http://www.sahivsoc.org/upload/documents/WHO%20Use%20of%20Efavirenz%20during%20pregnancy.pdf
as a recent reference from WHO on safety of efavirenz in pregmancy
low WBC and Neutrophils
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.