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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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Suppressed Saliva?
Mar 3, 2013

Hi, I'm on Complera. Does the medication reduce your saliva production? I have receding gums despite what I think is thorough, consistent, oral care; the dental hygeinist has noticed stringy saliva; harsh mouthwash & acids cause a problem; gums are even sore sometimes although drinking huge amounts of water seems to help with this. Why exactly is this happening & how can I make more saliva??

Response from Dr. Henry

Interesting question-I have not observed that problem in patients we have on Complera nor am I aware of a signal for oral problems from studies or the literatire (still quite limited since new drug). Many non-HIV drugs can have an anti-cholinergic effect (such as antihistamines and many psych drugs) that can cause dry mouth/decreased saliva production). If any reader is aware of a published paper noting a connection between Complera and decreased saliva, or has personal experience they would like to share-please post! KH

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