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switch back to stavudine?
Feb 6, 2013

can a patient who was switched from a stavudine-based regimen to a tenofovir-based regimen go back to the stavudine-based regimen, e.g., if the tenofovir-based drug is no longer available

Response from Dr. Henry

Generally in the setting of suppressed virus/good clinical response, tenofovir can be switched to stavudine when facing a shortage of tenofovir with a mild increase in risk for treatment failure and higher risk for side effects long term. Short term patients most often would do OK with the switch if the other drugs maintain good antiviral activity. KH



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