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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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tingling and numbness
Jan 25, 2013

I have been on Atripla going on 2 years this coming april, for about the past 6 months or so I have been experiencing sort of tingling and numbness in my legs. Could this be a side effect of this drug ?

Response from Dr. Henry

Peripheral neuropathy from HIV drugs usually starts first in toes/feet before involving the more proximal legs. The risk for neuropathy from HIV is higher in patients with now CD4 counts. Many non-HIV factors can cause numbness in legs including nerve impingement from disc problems, loss of fat resulting in more pressure on nerves in back /posterior leg regions, other health problems such as diabetes, vitamin defiencies, side effects of other drugs. Can be seen with Atripla but not commonly so usually some other cause. KH

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