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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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Started Isentress and have insomnia, sweating, hands itchy
Jan 10, 2013

I starting taking Isentress and Trizivir 6 days ago and can not sleep, sweat terribly and really jittery. Switched from Viricept and Trizivir to get around diarrhea. Numbers have been good. T cells 600+, und. virus. Should I stop taking. My doctor says to stick with and have sleeping pills. This is the worst I have felt in 20 years.

Response from Dr. Henry

Yikes-I have observed only a couple of patients that experienced sleep/nervous system problems from Isentress-not common but can occur occasionally. Often will diminish over several weeks but it may be worth discussing whether there are other options for you (ie etravirine or a boosted PI such as atazanavir or darunavir) exist depending on your treatment history, where you live (which drugs available), and whether there is any drug resistance. KH

fatty cheeks
Just started treatment

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