Jan 9, 2013
Hello, I am a healthy 46 year old male who is 22 years HIV+. I am on a new regiment of anti-virals. NORVIR, ISENTRESS, VIRAMUNE XR, and PREZISTA. Horrible night sweat, now on my 3 week. Never had these before. Thanks
Response from Dr. Henry
I would recommend discussing with your HIV provider without delay. Nite sweats have not been a prominent feature for side effects from those medications with little published data on that particular entire regimen. I assume that you have some degree of drug resistannce necessitating use of a more complex multi-class HIV regimen. Severe new night sweats (also recommend checking and recording body temperature regularly) merit a clinical evaluation for hidden infection or other condition in order to rule out other causes and allow a focus on your HIV drugs if no other cause seems likely. If one of your drugs is a possible cause then a methodical switching of drugs to alternative regimen is worth discussing. Would make sure liver, kidney and other major organs are fine with no clues indicating a serious reaction to the nevirapine or darunavir in particular (I assume there has been no rash developing?) KH
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