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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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A Drug Holiday
Oct 31, 2012

5 months ago, I took a break from taking all of my HIV medicines. I am on Reyataz, Norvir and Epizcom. During this time my T Cells remained constant around 814, however my viral load went from undetectable to 10,000. My doctor did a genotype and I have 4 slight mutations, but show no resistance to medications. I recently started my HIV meds again, and I'm having some rough side effects. Weakness, Depression, Headaches, Stomach Problems, Extreme Fatigue and lack of concentration. I am also on high doses of Prozac, Celexa and Klonapin due to the fact that I suffer from PTSD and severe depression. (I tried to commit suicide on 6/4/2012). Would starting the drugs again be causing a lot of the symptoms I am feeling??? Thanks for your help, Dave

Response from Dr. Henry

Your HIV drugs could be contributing to your symptoms and/or interacting with your psych meds in such a way to cause some symptoms. If you have no significant mutations you might consider an alternative HIV regimen that might have less side effects and drug interaction potential (ie raltegravir based regimen). KH

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