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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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Stomach bloating
Aug 20, 2012

Hi, I've been on truvada and isentress for the last 10 months and everything is going well apart from severe stomach bloating that is getting more frequent. I have been reading up on it and it looks like the truvada is causing it. I don't want to stop isentress so I was wondering what a suitable alternative to the truvada would be? I've read that Ziagen could be something to consider but I don't know anything about its possible side effects and affects on my body. I'm 55 and otherwise healthy. Any advice you can give would be much appreciated, I live in the UK. Thank you Mike.

Response from Dr. Henry

A small subset of patients on Truvada have ongoing GI symptoms (? < 5-10%). Abacavir as a substitute for the tenofovir is a reasonable alternative if HLA B5701 negative (a genetic test looking for increased risk for a hypersensitivity reaction). Abacavir otherwise is reasonably well tolerated-may have slightly higher lipid levels than seen with tenofovir but likely less of a negative effect on bone and renal health. KH

Chronic stomach pains
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