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PEP and lipodystrophy
Feb 17, 2012

Is it possible to get lipodystrophy during a 4 week course of PEP? I only have 4 more days left of my regimen. I've also been having pain and tingeling in my feet for quite some time and it's got noticeable worse while on PEP. I'm on Combivir and Kaletra if that makes any difference.

Response from Dr. Henry

Significant fat distribution problems from 4 weeks of PEP would be very unlikely and usually would be reversible after the 4 weeks if it did develop. Peripheral neuropathy can be seen with Combivir + Kaletra but not common over 4 weeks and again usually reversible if it does develop. KH

Dosage management, with the intention of minimizing side effects
Atripla + Silodosin & Rash

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