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Isentress: Tiredness ??
Feb 1, 2012

Doc: I first started with Atripla and had to come off it due to severe allergic rash. Then was put on Epzicom and Isentress. Have taken this for about 10 days. It seems to be making me very tired particularly in the afternoons. Have you found this to be common for those taking this combination. I realize I have to give it more time but would there be another regimen that would be as effective. (I take the Epzicom and Isentress at 6PM and the other dose of Isentress around 6 AM.) Thanks!

Response from Dr. Henry

Fatigue has been seen with raltegravir though rarely treatment limiting and often (though not always) easing up after first month. If continues to be a problem consider discussing with your provider whether a boosted protease inhibitor based regimen + Truvada or Epzicom might be an option for you. KH



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