Alkaline phosphatasis (AP) still climbing up
Dec 7, 2011
Dear Dr. henry: I wrote to you about six months ago, concerned about my AP levels. By that time I had 130 U/L. Other Liver/kidney tests were normal. I took another test on last friday and my AP is now 166 U/L. The remaing tests are still normal. I take efavirenz, lamivudine and tenofovir. I am in Haart therapy since 2001 and this is my second regimen (taking it for seven years - excepting tenofovir, about a year - replacing estavudine). I also take a drug to treat bipolar disorder (Trileptal) twice a day (900 mg). I am a 47 years old "heathy" HIV positive man who works out (three times a week) and practice judo (also three times a week). Should I be concerned about this new AP result? Best wishes, Sérgio
Response from Dr. Henry
Modest alk phosphatase increases are often of no clinical significance though can signal liver disease, bone problems, hormone problems (ie thyroid, parathyroid, adrenal) and many other conditions so a general health evaluation and following levels is recommended. Trileptal can increase some livere enzymes-your HIV regimen would rarely be the direct cause. KH
Get Email Notifications When This Forum Updates or Subscribe With RSS
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.