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Rash spreading after quitting Atripla
Dec 7, 2011

Hello, I stopped taking Atripla under doctor's orders once I saw that day 3 of rash was worse than day 2 inspite of the antihistamines prescribed. I stopped taking the atripla two nights ago and still the rash seems to be gaining force, spreading and getting very close to eyes, nose, mouth and private areas. Yesterday l went to the hospital to see my doctor and he gave me a cortisone shot and prescribed prednisone 30mg to take once a day for 3 days starting today. I woke up today with this rash looking and feeling worse and after taking my prednisone and antihistamine l still don't feel this is calming down. I am scared to wake up tomorrow with my eyes, mouth or vulva affected. Is there anything else that can be done? How long do these rashes increase in intensity after having quit the Atripla? I'm supposed to start my new regimen tomorrow but feel it's crazy to put any more "stuff" into my body the way it is now. Please let me know what your thoughts are, I'm very concerned. Thank you so much. E

Response from Dr. Henry

Rash from Atripla (usually the efavirenz) usually would start clearing within a week of stopping-if not requires careful monitoring and consideration of other cause (I agree awkward to start new meds when rash is getting worse but sometimes that is done to prevent resistance to the efavirenz). KH

Changing regiment and resistance
Alkaline phosphatasis (AP) still climbing up

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