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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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poz & insomnia
Aug 10, 2011

Im poz and am having sleepless nights. Have been taking Atripla for a year with no issues. But lately outta the blue IM having trouble falling asleep, and getting any sleep. Can I try Melatonin? I dont want to use prescription meds if I can help it.. Is it safe, ok to use with Atripla? Im thinking I can take Atripla about 8pm and Melatonin about 12 right before bed. Thanks.

Response from Dr. Henry

Occasionally patients report that they have developed problems sleeping after many months of doing well in Atripla. Changing the dosing to AM and observing impact on sleep and how well that is tolerated with worth considering on a trial basis after discussing with your HIV specialist. Looking for other causes of sleep disturbance is recommended as well. If not other likely cause found then use of a sleep aide (over the counter like melatonin or diphenhydramine OK or sometimes a prescription sleep enhancing drug) is worth discussing wth your HIV provider. In some cases, a trial switch off efavirenz (i.e. to another NNRTI, a boosted protease inhibitor, or raltegravir based regimen) may merit discussing with your HIV provider. KH

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