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HIV Treatment & Lipodystrophy
Feb 12, 2011

Hi Doctor,

I been on medication of Combivir + Stocrin since 2006. I recently found out that this regimen is contributing to lipodystrophy. I am quite concern about this and wonder is that any alternative treatment I can consider? I plan take some protein and work out in the gym and will this help? Any complication for lipodystrophy in the long run?

Thanks Fendy

Response from Dr. Henry

If available to you a switch from Combivir to Truvada (or Epzicom if HLA B5701 negative) often will slow/reverse fat loss. Effects on fat gain are more variable. Exercise and diet may help some patients so you should continue those healthy activities as well. The long term health implications of severe lipodystrophy are still unclear and are under study. Concern about effects on bone health, risk for heart disease, aging and other conditions makes lipodystrophy a priority in the HIV field. KH

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