Dec 22, 2010
I have been taking Atripla for approx. 1.5 years. I had a baby immediately prior and only took Reyataz and Truvada for the last two trimesters of pregnancy. This is the totality of my treatment experience. I have noticed a bit of fat accumulation around my belly and thinning in my legs and butt. Is this common on Atripla? Does it normally happen so quickly? Perhaps I am only picking up body changes associated with my pregnancy.
Is there another drug choice that lends itself less to body changes or is Atripla okay?
Response from Dr. Henry
Body fat changes (loss of fat= lipoatrophy and gain of fat= lipohypertrophy) is seen with HIV infection and also may be worsened by some HIV regimens. Atripla usually compares favorably to other HIV regimens in the degree of fat problems but they still occur. It is difficult to recommend an alternative regimen since so study to my knowledge (or in my own experience) has shown a clear benefit when switching from Atripla to another regimen. Drugs to at least consider might be raltegravir or mariviroc for the efavirenz but I say that with no good data. Switch options depend on availabilty and treatment history. In some cases family genetics may play a key role (comparing your body fat distribution to other family members without HIV can provide some clues there). Diet and exercise and other metabolic factors can also be involved so a clinical assessment focusing on those issues may be worthwhile as well. In many cases it may not be easy to address/reverse the situation given our current state of knowledge and limited effective treatment options. KH
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Itchy Rash During Seroconversion
- Sex With A Prostitute How Long Does It Take To Test Positive For AIDS
- Burning Urethra After Oral Sex Worried I Have HIV
- Painful Red Spots After Getting A Tattoo Worried I Have HIV
- Swollen Lymph Nodes After Giving Oral Sex What Are The Chances Of HIV
- Tingling Lips After Swallowing Worried I Have HIV
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.