|Safer Drugs for Prevention of mother to child transmission
Nov 10, 2010
My Girlfriend and I are Hiv positive with her CD4 at 480 and 720 for me. We do not at the moment take any ARVS but she is 17 weeks pregnant. She was told at the PMCTC clinic that she will start treatment at 28 weeks with COMBIVIR AND NEVIRAPINE. I am a Pharmacist and What I know is that although these two Drugs are more Toxic than The newer drugs such as Truvada and Kaletra, they are preferred choice for Prevention of mother to child transmission because their effectiveness and usage in this respect is very well Known. The newer protease inhibitors and Integrase inhibitors are not available in this part of Africa. Can I suggest to my prescriber to put her on Truvada and kaletra/Nevirapine at 28 weeks or she should start with their recommendation of Combivir and nevirapine and she can then switch to Truvada and Kaletra after delivery or do you have any other suggestion?
| Response from Dr. Henry
Combivir + Nevirapine has had lots of use in pregnancy but there are safety concerns if the CD4 count > 250 for women. In our clinic we often have used Kaletra (or other boosted protease inhibitor) + Truvada which can be a challenge to tolerate from the stomach standpoint but is effective for HIV control and avoiding resistance. KH
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Mother-to-Child HIV Transmission And Prevention
- What Drugs Are Used To To Prevent Mother-to-child Transmission Of Hiv?
- What Prevention And Control Strategy Can Be Used Avoid The Transmission Of Gonorrhea?
- Does Masturbating A Lot Have Side Effects?
- Drop In White Blood Cell Count
- How Long Can U Live With Hiv?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.