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Ketamine interaction
Oct 31, 2010

Dear dr. I've read that the efavirenz in atripla could increase amounts of ketamine in the blood. But could ketamine reduce levels of any component part of atripla? Thank you

Response from Dr. Henry

Though both efavirenz and ketamine are metabolized in the liver, I am not aware of a clear clinically significant interaction between the two drugs.There may be a more significant interaction between protease inhibitors and ketamine that bears close attention if those drugs are being considered to use together. KH

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