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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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How bad is Isentress
Sep 13, 2010

I have been on Isentress for about a month. It seems that Abnormal Dreams, Insomnia, Fatigue are MAJOR side effects. In general do they get better over time and any idea (knowing that everyone's body is different) about how long are we talking before easing up?

Response from Dr. Henry

Such central nervous system side effects from raltegravir are not frequent but can be annoying. Such side effects occured lest often in patients taking raltegravir (10%) then in a comparison group taking efavirenz (ie component in top selling drug Atripla). Long term outcome somewhat unclear to me since I have not observed that problem much in our clinic and not much is published in the literature. If any reader knows of a reference or has personal experience please post. KH

Should I switch medications?
pain and swelling in left hand

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