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| Management of Norvir Side effects: Abdominal/Back pain Jun 30, 2010 Are there any tip or tricks to managing abdominal/lower back pain related to taking Norvir? I take this drug I gelcap 2 times a day and am after one week experiencing relatively intense abdominal cramping and lower back pain which is about 8 on a scale of 1-10 and makes it difficult to sit comfortably or to stand up from a sitting position. Should I expect this to diminish? Can I do anything? When should I speack to my Dr.? I had to stop a regimen including Kaletra after 7 years due to severe diarrhea and I don't want to have to stopp this too. |
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Response from Dr. Henry
Often no easy answer to managing ritonavir side effect. Checking to see if is possible to reduce the dose (some protease inhibistors only require 1 100 mg ritonavir dose/day) of ritoanvir can be helpful. Anti-gas, calcium supplements, fiber capsules, macrobiotics-all may help variably. If nothing helps then a review of what antiretroviral switch options (ie a NNRTI or raltegravir or maraviroc based regimen) you have is warranted. For patients with no drug resistance a non-ritonavir based PI regimen (such as atazanvir with Epzicom or fosamprenavir). I would involve your HIV doc early in the discussion given the amount of discomfort you are experienceing. An evaluation looking for contributing conditions may also have merit. KH | |||||||||
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