Dosage of cetirizine to control Atripla rash
May 28, 2010
Hi, Started Atripla 18 days ago and around day 8 woke up to itching of my feet, treated that with hydrocortisone cream but by day 10 the itch and accompanying rash was quite noticeable on hands and feet so I went to my HIV clinic and they felt this was a fairly standard rash attributable to the efavirence in the Atripla and they gave me a prescription of cetirizine (Zyrtec) to take 10mg daily. I immediately took one (around lunch) and within a few hours all itching had stopped and the rash had subsided just a tiny bit. However by nightime the ithing was back and I was unable to sleep until I took another 10mg pill. Basically my rash has continued to develop (arms, knees, feet, parts of back, neck and a bit of swelling and redness on face). I can live for now with the visual but the ithing I cannot and to hold the itching at bay I am using between 20-30mg of cetirizine a day at the moment. Bearing in mind that I am hoping this to be a one-off event over in a week or two are there any serious implications (both from an HIV medication point of view or otherwise) that I should be aware of from upping my antihistamine dose above the daily recommended dose of 10mg? Alternatively is there something more effective in managing the ithiness of the rash associated with efavirenz?
Response from Dr. Henry
Often diphenhydrammine (25 mg 2-3 x day) can be helpful in that situation (either in addition to once a day cetirizine or instead of). Often will take 1-2 weeks for rash to run its course. If eyes, mouth, breathing involved need to contact your HIV clinic promptly. KH
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Pain In Penis After Having Sex During Period What Are The Chances Of HIV
- Swollen Lymph Glands After French Kissing Worried I Have HIV
- How Long Do You Have To Wait Until You Can Get Tested For An Std?
- Stress Cause A Abnormal Pap Smear
- 14 Months After Possible Exposure Results Non Reactive
- 7 Week Negative Rapid Blood Test After Low Risk Exposure
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.