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Atripla and ALRI Poison Fat Burning Supplement
May 22, 2010

Hi Doctor,

I've bought these fat burning supplement pills, and I take Atripla once every night for my HIV. Do any of these ingredients ring any alarm bells in terms of drug interaction with atripla? I am specifically worried about the bit where it says do not take if you are taking a MAO-B inhibitor (is that part of Atripla).

Thank you very much. Damien

Poison Supplement Facts Serving Size: 1 Dual Release Tablet Servings per Container: 30

Amount Per Serving % Daily Value Uniquie Propietary Matrix:

R-N-Benzyl-alpha-phenylethylamine HCL, Quercitin, R-beta-methylphenylethylamine HCL, Caffeine Anhydrous, Olive Oil Concentrate (98% Hydroxytyrosol/Tyrosol), Glycine sinensi concentrate (from leaves), Piperine, Yohimbine from Rauwolfia Serpentina Concentrate, Sophora Radix Concentrate 935mg **

* Percent Daily Values are based on a 2000 calorie diet. ** Percent Daily Values not established.

OTHER INGREDIENTS: Microcrystalline Cellulose, Dextrose, Hydroxypropylmethylcellulose, Dicalcium Phosphate, Sodium Starch Glycolate, Magnesium Stearate, Stearic Acid, Silica, FD&C Blue #1, FD&C Red #40

Poison Directions: As a dietary supplement, take 1 tablet in the morning with food. To avoid sleepnlessness, avoid taking Poison after 12 p.m. Do not take more than 1 tablet in a 24-hour period. Do not use more than 4 weeks without a 2 week break in between.

Poison WARNING: This product is only intended to be consumed by healthy adults 21 years of age or older. Before using this product, seek advice from a physician. Avoid using this product if you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney, or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAO-B inhibitor or any other medication or supplement. Do not use if you are pregnant, nursing, prone to dehydration or exposed to excessive heat. Discontinue use and consult your health care professional if side effects occur. Do not exceed recommended serving size. . Individuals who consume caffeine with this product may experience serious adverse health effects and those that are sensitive to the effects of caffeine should consult a Physician before consuming this product. Drink at least 2 liters of water daily and consume adequate calories when using this product. This product should be used in conjunction with proper diet and exercise. KEEP OUT OF REACH OF CHILDREN.

Response from Dr. Henry

Atripla does not contain a MAO inhibitor. Efavirenz is metabolized by the liver so one does have to watch for side effects. I recommend bringing in the fat burning supplement (none of which have been proven to be safe and effective long term) to be reviewed by your HIV specialist or pharmacist. KH



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