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Are there any Neuroplasticity studies for individuals with resolved Encephalopathy?
Mar 4, 2010

Dr Keith, My partner had encephalopathy now resolved for several years. It left him with left side motor dysfunction and balance related problems. There are other mental aptitude factors as well. Has anyone done any neuroplasticity studies with patients who have suffered neurological damages more specifically related to Encephalopathy? Are there any efforts to engage such studies? The Drake Center in Cincinnati is presently engaged in NIH grant funded Neurological plasticity studies with patients who have had long past stroke recovery but no neuro therapy to retrain their brain prior to now. Thank you for taking time out of your busy schedule to consider my question! Sincerely, Barry

Response from Dr. Henry

Good questions-brain damage related to HIV infection can take numerous forms. In some cases the (such as from PML or lyphoma) the damage is similar to the structural damage from a stroke so recovery depends on location and size of lesions. If more diffuse from HIV then recovery depends on how extensive is the involvement, how well HIV replication is controlled in blood and brain, and often presence of other factors.Direct treatment of brain injury other than indirect control of HIV infection or treatment of complicating infections has been disappointing. If any reader knows of any study with HIV+ patients using regenerative approaches (neuroplasticity) please post! KH



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