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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
          
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Potential side effects
Jun 21, 2009

Dr.,

My doctor switched me from Atripla (2 years undectectable) to a new combo because of a recent viral load jump from undectectable to 2,600. The new combo is: Zidovudine - 300 mg 2x / day Viread - 300 mg 1x / day Reyataz - 300 mg 1x / day Norvir - 100 mg 1x / day

I've had problems with fasial wasting in the past but it was under control with the Atripla. What is the potential for fascial wasting with this new combo?

Response from Dr. Henry

There may be a modest increased risk for facial wasting due to the zidovudine but there is very little data published on your particular combination. Aging, lower CD4 counts, and uncontrolled HIV replication may contribute to facial wasting so use of a more effective regimen can have mixed effects so often hard to sort out or predict what will happen for an individual patient. KH



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