jaundice and management
Apr 17, 2009
i have been on ARVs since august 2008. i reacted to the fisrt line and had to stop for two weeks then changed to Effeverac and CT3. i have now developed jaundcie and told to stop. I know my CD 4 will get down how to i maintain it and manage the jaundice for now .can i resume the treatment
Response from Dr. Henry
Stopping efavirenz can lead to resistance. An evaluation of liver status/hepatitis serologies is recommended. If available recommend using a boosted protease inhibitor for several weeks after stopping efavirenz based therapy. Often flare-ups of liver enzymes can be seen when starting various HIV meds so generally stopping and starting is discouraged -try to treat through the liver enzyme flare-ups (if mild or moderate) while checking out what elso is going on and seeing if alternative HIV meds are available if it looks like a particular HIV med is contributing. KH
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