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Tenofovir on hair and bone

Mar 15, 2009

Curious student from Africa: Is TDF actually distributed into hair, and what is the mechanism for hairloss? What is the probability of increased bone turnover within the first six months of use? Is there any data?

Response from Dr. Henry

I haven't seen any data on tenofovir in hair or having much of an effect on hair growth. The effect of tenofovir on bone turnover/loss in adults has generally been very minimal (very mild bone loss)over first 1-5 years of use but longer term studies are needed since even a mild effect could be clinically meaningful after several decades.KH

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