Drug Induced Neuropathy
Mar 11, 2009
I have taking Truvada for the past 3 yrs along with Lexiva started about a yr ago. I have had numb toes which is progressively worsening for the past 8 months. I know Truvada has a low probability of causing neuropahty. If a drug is the offender typically how long does it take before symptoms appear? Could it be the Truvada and took a couple of years before I became symptomatic? Or is it more likely the Lexiva which was introduced 12 months ago? I am trying to isolate the culprit
Response from Dr. Henry
Recommend getting a full evaluation (including looking at vitamin deficiencies, diabetes status, et cetera) and possibly a neurology consult to better define the nature/extent of the peripheral neuropathy. Individual components of your regimen can rarely contribute to peripheral neuropathy. If no other cause found then a careful switching to alternative HIV meds (perhaps one drug at a time) is worth considering. KH
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