Feb 4, 2009
Hi Dr,i would like to know which a ARV drug is causing hiccup side effect,how is the mechanism?
Response from Dr. Henry
To my knowledge no HIV drug has been linked to hiccups (fairrly common in general population) which often relate to some form of vagal/phrenic nerve or diaphragm irritation. A wide range of non-HIV related conditions can trigger hiccups. Treatment can be frustrating and quite variable in effectiveness but often includes measures to increase CO2 levels or vagal nerve/carotid sinus stimulation. Numerous drugs can sometimes provide benefit (such as metocloprmaine or chlorpromazine). KH
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