Feb 4, 2009
Hi Dr,i would like to know which a ARV drug is causing hiccup side effect,how is the mechanism?
| Response from Dr. Henry
To my knowledge no HIV drug has been linked to hiccups (fairrly common in general population) which often relate to some form of vagal/phrenic nerve or diaphragm irritation. A wide range of non-HIV related conditions can trigger hiccups. Treatment can be frustrating and quite variable in effectiveness but often includes measures to increase CO2 levels or vagal nerve/carotid sinus stimulation. Numerous drugs can sometimes provide benefit (such as metocloprmaine or chlorpromazine). KH
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