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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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Neuropathy in my feet?
Dec 21, 2008

I have been positive for 19 years and have had neuropathy in both legs since Feb 91.

At one time Desipramine and Mexitil worked to help manage the pain along with Kadian.

Currently I take 400 mg of Kadian for my leg pain with Dilaudid for breakthrough pain. My viral load has been undetectable for years and my t-cells are around 260 with my percentage stable at 25%.

I take Intellence, Isentress, Prezista and Norvir for treatment.

A few days ago, my feet started to hurt. Now they have tingling, numbness and pain in them, and they feel cold, but they are warm.

The 400 mg Kadian I take does not have any pain relief in my feet. It hurts to wear shoes or stand very long.

Could this be neuropathy in my feet now?

I used to be in a wheelchair before we got my PN pain under control. I really don't want to go back.

I'm afraid at the rate it's progressing that I won't be walking in a couple days.

Response from Dr. Henry

Peripheral neuropathy remains one of the most challenging HIV-treatment related conditions to manage since often patients need to continue to take possibly offending meds from the HIV/AIDS standpoint. Your current regimen has not been linked to an excessive risk for peripheral neuropathy but there is a low rate that has been seen in pxs on similar combinations that is difficult to sort out since pxs are on numerous medications and may also have contributing conditions (such as diabetes or restless leg syndrome). I would inform your HIV specialist immediately so he/she can decide how to manage the discomfort and what options there are to switch off any possibly associated medications. KH

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