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Muscle cramps and stiffness Nov 23, 2008 I have been experiencing muscle stiffness, soreness and cramps for about a month. My HIV medications have not changed in 6 months, but other medications have been added by different doctors. Currently Im taking Epzicom + Reyataz + Norvir; also 300mg Effexor XR, 300mg Seroquel (added recently), 1gm Valtrex, 150mg Doryx (added recently), and 25mg Lopressor. Ive noticed that I tire easily and the number of times I have to urinate has increased. Can you offer any insight into which of these medications could be causing the muscle issues? |
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| Response from Dr. Henry
 The protease inhibitors you are taking can increase the levels of the Effexor and Seroquel leading to increased risk for side effects-some anticholingergic side effects can include bladder dysfunction. A general health evaluation including checking an EKG, muscle enzymes, urinary tract status is recommended with those meds and symptoms. KH | |||||||||
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