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Is Mk-677 a viable treatment?
Nov 6, 2008

I am a researcher and recently came across an article on demonstrating an upregulation of HGH with supplementation of Mk-677 in frail older adults. Has this treatment been used in HIV+ individuals and if so, has it been effective in reducing wasting?

Response from Dr. Henry

I haven's seen in clinical studies in HIV+ persons using MK-677. Growth hormone releasing factor has been studied in humans (needs to be injected) with HIV-related abdominal fat accumulation with modestly promising results and a safety profile over 6-12 months. If any reader is aware of a reference using MK-677 in HIV+ persons please post. KH

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