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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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Oct 24, 2008

Hello Dr.KH I been on Kaletra and Truvada since July 08, they are working great, my CD500-VL 750, I been experience stomach issues like , bad taste in my mouth ,some occasionally explosive diarrhea, felling nauseas , stomach pain and heartburn, also my triglyserites are high on 300 all this it really bothers me allots . this side effect are part of this combo? I want to ask the Doctor to maybe change meds. am allergy to Sustiva , any advice.

Response from Dr. Henry

Some patients have GI complaints as you describe from boosted protease inhibitors. Sometimes a switch to an alternative boosted PI (such as to atazanavir) might decrease the symptoms. The tenofovir in Truvada also can occasionally cause ongoing stomach complaints . A switch to an alternative boosted-PI, nevirapine, or raltegravir may warrant consideration depending on your treatment/resistance history. KH

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