The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App 
Professionals >> Visit The Body PROThe Body en Espanol
Ask the Experts About

Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
Rollover images to visit our other forums!
Recent AnswersAsk a Question
  • Email Email
  • Glossary Glossary

Isentress and high histamine levels

Oct 19, 2008

I was recently tested for my neurotransmitter levels and my histamine level was double the high end of high. Ever since I started taking Isentress in December 2007 I've been anxious, depressed, and obsessive. I've read a few comments on here about psychological effects experienced by users of Isentress but they're vague and non-specific. Is there any information available here or elsewhere about this subject? Thanks.

Response from Dr. Henry

There has been a small number of reports of increased depression in patients taking raltegravir (Isentress). I have not seen anything offering a clear possible mechanism. The overall rate of depression linked to raltegravir has been low and depression is common in the general and HIV+ population so a modest link to a particular drug (even more true when used in combinations of drugs) can be difficult to establish-thus the vague and non-specific data that mention (frustrating to many!). KH

black pigments
PEP Related questions

  • Email Email
  • Glossary Glossary

 Get Email Notifications When This Forum Updates or Subscribe With RSS



This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint