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switching combivir to truvada
Aug 6, 2008

I have been on kaletra and combivir combination for 2 years. I have undetectable viral load and no serious side effects.My doctor suggested me that changing combivir to truvada. I actually want to change combivir to truvada because of the risk of lipodystropy and easier to use(one a day dose). My question is, if i can not tolerate or develop resistance to truvada ,is it possible to to back to combivir? I don't want to lose my previous regimen.

Thanks. Tetu

Response from Dr. Henry

Most patients do well with a switch from Combivir to Truvada from both the tolerability and resistance standpoint. If you encounter a problem tolerating Truvada often you could be switched back to Combivir (or consider Epzicom particularly if HLA B5701 negative) unless your viral load was increasing. KH



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