|Atripla and Possible Sleep Paralysis Induced
Apr 18, 2008
I'm undetectable, T-Cell count of 849 and CD4 % greater than 25.
I have taken Atripla for nearly 1 year. Over the past 6 to 9 months, I have been experiencing Sleep Paralysis 2 to 3 times a week. Sometimes, the paralysis will continue for several episodes in a single night, especially from 4am to about 6am. I take Atripla every night at 10pm. Is this a possible side effect since I have never experienced side effects previously?
The only change has been medication. Prior to Atripla, I was taking Sustiva and Combivir for 3 years. I was diagnosed in 2003.
The Sleep Paralysis can be scary. I feel that I am awake, but I can't open my eyes, can't move my body, sometimes I can mumble in hopes my dog or my partner will hear me and shake me awake. Any advice will be helpful.
| Response from Dr. Henry
Interesting situation. Certainly efavirenz can occasionally cause lingering highly annoying brain side effects. I would consider a sleep study/evaluation by a sleep expert and/or a trial of an alternative HIV regimen (ie Truvada + a boosted protease inhibitor based regimen) for several months to try and see if the effect is caused by the efavirenz. KH
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