|Is folliculitis a side-effect of Kaletra
Feb 11, 2008
I was on Truvada and Viracept since I started treatment. Viral load had been undetectable and CD4 in the 400 range. My doctor informed me that there had been a study done that indicated that Viracept was a carcinogen and advised that I switch to something else. At the beginning of January 2008, I started using Kaletra. After being on the Truvada and Kaletra combo for approximately two weeks, I developed severe folliculitis on most parts of my body. Currently, being treated with oral and topical antibiotics. No new labs done yet. Is this just a coincidence that I got folliculitis at that same time I've been on my new regimen or could the Kaletra be the cause? I'm convinced it's the Kaletra. Any advice?
| Response from Dr. Henry
The issue with Viracept was that the formulation available in much of the world contained a contaminant (EMS) that has been linked to health concerns including a potential increased risk for malignancy (lifetime risk estimated to be 1 in 100,000 which is still low overall). To my knowledge that problem has been addressed. I have had numerous patients on Kaletra experienced flare-ups of folliculitis either when starting ART for the first time or switching from another treatment. If is unclear to me whether those flare-ups related to further immune restoration or are due to one of the components of Kaletra. Folliculitis is fairly common in HIV+ persons so could also not be related to either of those possibilities so it is often hard to pin down why the flare ups occur. If stumped I often refer to a dermatologist to try and narrow down the diagnostic possibilities. KH
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