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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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Nov 18, 2007

i take kaleetra,combivir,and viread since i was diagnoised in was rough till i got use to doing fine..viral load undetectable..cd4 i,m about to change to atripla to make life simpler..will my change be easier on this drug or about the same nasty effects can be expected first hand as with my current drugs??i,m scared to death thing about it...Help!!

Response from Dr. Henry

The side effect profile for Atripla is quite different than with your current regimen. Most patients would experience fewer side effect with Atripla which is one reason why it has been so successful. Patients particularly have fewer gut side effects and less anemia with Atripla compared to your regimen of Kaletra/Combivir/Viread. The major side effect category for Atripla related to the central nervous system (brain). The efavirenz in Atripla causes a significant percentage of patients to have sleep/dream abnormalities, foggy or fuzzy thinking, or other symptoms during the first 2-4 weeks (better tolerated for most patients if taken before bedtime). After 4 weeks perhaps 10% of patients continue to experience annoying side effects of that nature. KH


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