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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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MAC Treatment
Oct 23, 2007

I developed a nasty case of MAC as a result of IRIS when I started my HAART. It has now been well over 2 years and my VL has been undetectible for over a year and my CD4 count is 400+/-. How long should I have to take the Clarithromycin? (one tablet/day)

Response from Dr. Henry

Good question. Most studies and experience suggest that MAC prophylaxis or treatment can be stopped after two years and good immunologic/virologic status like you have experienced. There is less published on MAC manifested as IRIS but the same general principles should apply . Your HIV specialist who has followed you through the last 2 years if usually the best source of advice since he/she is aware of any nuances applying to your situation. KH

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