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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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Oct 23, 2007

Hi, I have been taking a combination of Truvada and Stocrin from the beginning of my treatment (February 2007). Though the drugs are working fine (780 CD4, undetectable), recent lab tests show an increasing problem with my liver. My doctor has suggested that I switch to Trizivir (once a day). Can I trust that my new treatment would be as effective as the previous one - without affecting my liver. I am supposed to start the new treatment next month. Also, can I take a break from the actual medication before I switch to the new one? Many thanks K.

Response from Dr. Henry

I do not advise stopping your current meds before trying an alternative regime. That could lead to the development of resistance or a flare of HIV-related conditions. I don't have much confidence that Trizivir would be clearly less harmful to your liver than Stocrin and Truvada. It Trizivir is used it generally should be dosed twice daily and not once daily. KH

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