|PEP for 2 weeks with Slight Lab Abnormalities--Stop or Decrease Dose?
Oct 5, 2007
Hi I had receptive unprotected anal sex with someone of unknown status. My doctor started me on PEP program 24hrs later with Epivir, Retrovir, and Kaletra. I had lots of fatigue and side effects so Kaletra was decreased to one tab twice a day from the two tabs about 5 days into course. I had baseline labs which were all normal, including HIV. 2 weeks into PEP, i had labs which are borderline abn: bun 21 (nl <19)/creatnine 1.2 (nl < 1.3), ast 52 (nl <40), alt 67 (nl <35), and wbc 3.5 (nl >4), otherwise everything else was normal. The fatigue is manageable but my doctor is recommending decreasing the dosages further of the epivir and retrovir but I am worried about the efficacy of PEP at this point....are these lab values really so abnormal that i should decrease PEP or should i just continue on for two more weeks without worry? please help
| Response from Dr. Henry
Those labs alone would not sway me to make a recommendation to stop PEP. That decision would be based on the details of the exposure and the magnitude of your side effect symptoms. The effectiveness of 2 weeks of PEP has not been well studied/demonstrated so cannot be generally recommended if prevention of infection is the main goal. KH
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Abnormal Lab Values For HIV/AIDS
- Does Abnormal Lab Values Mean U Have Hiv Or Herpes?
- Black Spots After Rimming Worried I Have HIV
- Muscle Ache After Giving Oral Sex Does It Mean I Have HIV
- Pain In Balls After Drinking After Someone Sign Of HIV AIDS
- Sore On Penis After Mutual Masturbation Worried I Have HIV
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.