Sep 27, 2007
what are the longterm sideeffects og kaletra reyataz norvir and truvada?
Response from Dr. Henry
The most common short term side effects for Kaletra are bloating,cramping, gas, and loose stools; for Reyataz less of those but mild jaundice (yellowing of skin or eyes), for Norvir same as Kaletra but less frequent or severe when used as a booster @ 100 mg dose; for Truvada it is loose stools, mild nausea, skin changes or low rates of a variety of complaints. Long term side effects for Kaletra are often related to elevations in lipids such as cholesterol or tryglycerides (same true to a less extent for Nrovir). Reyataz has not been studied much long term but appears well tolerated/safe except for the small percent who develop more severe jaundince (< 5%). Truvada (tenofovir component) may cause renal problems in a small subset particularly in persons at risk for renal disease already (extent of renal dysfunction still being studied). This website has a good discussion about each of the drugs (click under treatment and then link for drugs). Another good source for drug information is the website is www.aidsinfonet.org or www.tpan.com . KH
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