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Managing Side Effects of HIV TreatmentManaging Side Effects of HIV Treatment
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Husbands new meds
Apr 25, 2007

My husband has been on many different hiv drugs over the years. When I met him he was on combivir, viracept and sustiva. They found those were no longer working and put him on kaletra, viread and didanosine. After being on those meds for a couple months he ended up in the hospital with pancreatitis. They took him off those meds and put him on norvir, reyataz, ziagen and emtriva. He is now saying he is having some of the same symptoms with his pancreas as when he was on the other meds. Can these meds effect his pancreas also? The doc has pretty much said these are the last meds for him and he is really worried. Any help and advice you can give us would be greatly appreciated.

Response from Dr. Henry

His current regimen has not been linked to a clear increase in pancreatitis though once the pancreas has been irritated a range of factors can cause flare-ups (such as high triglycerides partly due to some HIV regimen or HIV infection itself). In the US at least there are an increasing number of treatment options likely useful in this setting including use of daurunavir as the PI, Fuzeon (injectable-not linked to pancreatic problems), and soon to be approved CCR5 and intergrase inhibitors. KH

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